MESOTHELIOMA MALIGNA

Patogenesis mesothelioma maligna :
1.Debu asbes à mengiritasi pleura à jaringan parut.
2.Serat asbes à memutuskan gelondong sel mitotic à aneuploid dan kerusakan kromosom.
3.Debu asbes à iron related reactive oxygen species à kerusakan DNA.
4.Debu asbes à fosforilasi MAP kinase dan ERK 1 & 2.

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TUMOR PLEURA

The Pleura tumour was the Tumour that was diruang between the lungs and the cavity dada
the Pleura Tumour:
Primary: - Jinak
- Ganas
Secondary: resulting from metastase
the Other Pleura Tumour.
ANATOMY AND FISIOLOGI
the Pleura consisted two membranes:
1.Parietalis
2.Visceralis
the pleura Membrane consist of a layer of the cell mesothel.
To pleura space was gotten the pleura liquid.